HSD17B2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11304
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | 17 beta HSD 2,17-beta-HSD 2,17-beta-hydroxysteroid dehydrogenase type 2,20 alpha HSD,20 alpha hydroxysteroid dehydrogenase,20 alpha-hydroxysteroid dehydrogenase,20-alpha-HSD,DHB2,E2DH,EDH17B2,Estradiol 17-beta-dehydrogenase 2,HSD17,Hsd17b2,Hydroxysteroid (17 beta) dehydrogenase 2,Microsomal 17 beta hydroxysteroid dehydrogenase,Microsomal 17-beta-hydroxysteroid dehydrogenase,SDR9C2,Short chain dehydrogenase/reductase family 9C,member 2,Testosterone 17 beta dehydrogenase,Testosterone 17-beta-dehydrogenase,HSD17B2抗体 |
| Swissprot | P37059 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human HSD17B2 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | 17β-HSD2 (17β hydroxysteroid dehydrogenase type 2) belongs to the 17β-HSD family of proteins that regulate the availability of steroids within a tissue. 17β-HSD2 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and testosterone. Due to the affects that 17β-HSD2 has on the availability of estrogen, it has been extensively investigated for playing a possible role in breast tumor development, colon cancer development and the pathophysiology of endometriosis. |
Images
Western Blot analysis of Human fetal liver tissue using HSD17B2 Polyclonal Antibody at dilution of 1:300
Immunohistochemistry of paraffin-embedded Human esophagus cancer using HSD17B2 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human brain using HSD17B2 Polyclonal Antibody at dilution of 1:50
