HSD17B8 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11301
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | 17 beta HSD 8,17 beta hydroxysteroid dehydrogenase 8,17-beta-HSD 8,17-beta-hydroxysteroid dehydrogenase 8,17-beta-hydroxysteroid dehydrogenase VIII,3-oxoacyl-[acyl-carrier-protein] reductase,3-oxoacyl-acyl-carrier protein reductase,E. coli,homolog of,Beta ketoacyl [acyl carrier protein] reductase like,D6S2245E,DHB8,dJ1033B10.9,Estradiol 17 beta dehydrogenase 8,Estradiol 17-beta-dehydrogenase 8,Estrogen 17 oxidoreductase,FABG,FabG,E. coli,homolog of,FabG-like,FABGL,H2 KE6,H2-KE6,HKE6,HSD17B8,Hydroxysteroid (17 beta) dehydrogenase 8,Ke-6,KE6,KE6,mouse homolog of,Protein Ke6,Really interesting new gene 2 protein,RING2,SDR30C1,Short chain dehydrogenase/reductase family 30C member 1,Testosterone 17 beta dehydrogenase 8,Testosterone 17-beta-dehydrogenase 8,HSD17B8抗体 |
| Swissprot | Q92506 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human HSD17B8 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion matrix. |
| Tissue specificity | Highly expressed in placenta, liver and pancreas, lower in the skeletal muscle and kidney. Widely expressed. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. |
Images
Western Blot analysis of Human testis tissue using HSD17B8 Polyclonal Antibody at dilution of 1:650
Immunohistochemistry of paraffin-embedded Human liver cancer using HSD17B8 Polyclonal Antibody at dilution of 1:55
Immunohistochemistry of paraffin-embedded Human Kidney using HSD17B8 Polyclonal Antibody at dilution of 1:100(Elabscience® Product Detected by Lifespan).
Immunohistochemistry of paraffin-embedded Human liver cancer using HSD17B8 Polyclonal Antibody at dilution of 1:100(Elabscience® Product Detected by Lifespan).
