HSD3B2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19259
宿主: Rabbit
反应性: H,M
应用: WB
Overview
Synonyms | Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- And Steroid Delta-Isomerase 2,3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type II,Short Chain Dehydrogenase/Reductase Family 11E, Member 2,3-Beta-HSD Adrenal And Gonadal Type,3-Beta-HSD II,3 Beta-Hydroxysteroid Dehydrogenase Type II, Delta 5-Delta 4-Isomerase Type II, 3 Beta-HSD Type II,3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 2,3-Beta-Hydroxy-Delta(5)-Steroid Dehydrogenase,3-Beta-Hydroxy-5-Ene Steroid Dehydrogenase.,HSD3B2抗体 |
Swissprot | P26439 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Fusion protein of human HSD3B2 |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:500-1:2000; |
Concentration | 0.6mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Endoplasmic reticulum,endoplasmic reticulum,endoplasmic reticulum membrane,smooth endoplasmic reticulum membrane,Mitochondrion,mitochondrial inner membrane,mitochondrial intermembrane space,mitochondrial membrane,Other locations:integral component of membrane |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. |