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HSD3B2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19259

宿主: Rabbit

反应性: H,M

应用: WB

  • 详情
  • Overview

    Synonyms Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- And Steroid Delta-Isomerase 2,3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type II,Short Chain Dehydrogenase/Reductase Family 11E, Member 2,3-Beta-HSD Adrenal And Gonadal Type,3-Beta-HSD II,3 Beta-Hydroxysteroid Dehydrogenase Type II, Delta 5-Delta 4-Isomerase Type II, 3 Beta-HSD Type II,3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 2,3-Beta-Hydroxy-Delta(5)-Steroid Dehydrogenase,3-Beta-Hydroxy-5-Ene Steroid Dehydrogenase.,HSD3B2抗体
    Swissprot P26439
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Fusion protein of human HSD3B2
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:500-1:2000;
    Concentration 0.6mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Endoplasmic reticulum,endoplasmic reticulum,endoplasmic reticulum membrane,smooth endoplasmic reticulum membrane,Mitochondrion,mitochondrial inner membrane,mitochondrial intermembrane space,mitochondrial membrane,Other locations:integral component of membrane
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.
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