HSD3B2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15114
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | HSDB,HSD3B,SDR11E2,HSD3B2抗体 |
| Swissprot | P26439 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human HSD3B2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:25-1:100 |
| Concentration | 0.2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Endoplasmic reticulum,endoplasmic reticulum,endoplasmic reticulum membrane,smooth endoplasmic reticulum membrane,Mitochondrion,mitochondrial inner membrane,mitochondrial intermembrane space,mitochondrial membrane,Other locations:integral component of membrane |
| Tissue specificity | Expressed in adrenal gland, testis and ovary. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. |
