本公司产品仅供体外研究使用,不用于临床诊断

HSP105 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-10380

宿主: Rabbit

反应性: H,M,R

应用: WB

  • 详情
  • Overview

    Synonyms Antigen NY CO 25,Antigen NY-CO-25,DKFZp686M05240,Heat shock 105kD alpha,Heat shock 105kD,Heat shock 105kD beta,Heat shock 105kDa protein 1,Heat shock 105kDa protein,Heat shock 105kDa/110kDa protein 1,Heat shock 110 kDa protein,Heat shock 110kDa protein,Heat shock protein 105 kDa,HS105,HSP105,HSP105A,HSP105B,HSP110,HSPH 1,Hsph1,KIAA0201,NY CO 25,HSPH1抗体
    Swissprot Q92598
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Recombinant protein of human HSPH1
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:500-1:2000;
    Concentration 0.2 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm.
    Tissue specificity Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background Heat shock protein 105 kDa is a protein that in humans is encoded by the HSPH1 gene.Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly.Inhibits HSPA8/HSC70 ATPase and chaperone activities.Highly expressed in testis.Present at lower levels in most brain regions, except cerebellum.Overexpressed in cancer cells.Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.
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