HSP105 Polyclonal Antibody
| 规格: | / 20μL / 60μL / 120μL / 200μL |
| 价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-10380
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | Antigen NY CO 25,Antigen NY-CO-25,DKFZp686M05240,Heat shock 105kD alpha,Heat shock 105kD,Heat shock 105kD beta,Heat shock 105kDa protein 1,Heat shock 105kDa protein,Heat shock 105kDa/110kDa protein 1,Heat shock 110 kDa protein,Heat shock 110kDa protein,Heat shock protein 105 kDa,HS105,HSP105,HSP105A,HSP105B,HSP110,HSPH 1,Hsph1,KIAA0201,NY CO 25,HSPH1抗体 |
| Swissprot | Q92598 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human HSPH1 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. |
| Tissue specificity | Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Heat shock protein 105 kDa is a protein that in humans is encoded by the HSPH1 gene.Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly.Inhibits HSPA8/HSC70 ATPase and chaperone activities.Highly expressed in testis.Present at lower levels in most brain regions, except cerebellum.Overexpressed in cancer cells.Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity. |
