HSPA8 Monoclonal Antibody
| 规格： | / 20μL / 60μL / 120μL |
| 价格： | / ￥580 / ￥1420 / ￥2310 |
货号：E-AB-22161
宿主: Mouse
反应性: H,M,R
应用: WB,IHC-p
Overview
| Synonyms | 2410008N15Rik,Constitutive heat shock protein 70,Epididymis luminal protein 33,Epididymis secretory sperm binding protein Li 72p,Heat shock 70 kDa protein 8,Heat shock 70kD protein 10,Heat shock 70kD protein 8,Heat shock 70kDa protein 8,Heat shock cognate 71 kDa protein,Heat shock cognate protein 54,Heat shock cognate protein 71 kDa,Heat shock protein 8,Heat shock protein A8,Heat shock protein family A (Hsp70) member 8,Heat-shock70-KD protein 10,formerly,HEL 33,HEL S 72p,HSC54,HSC71,Hsc73,HSP71,HSP73,HSP7C,HSPA10,HSPA8,LAP1,Lipopolysaccharide associated protein 1,LPS associated protein 1,LPS associated protein,MGC102007,MGC106514,MGC114311,MGC118485,MGC131511,MGC29929,N-myristoyltransferase inhibitor protein 71,NIP71,HSC70抗体 |
| Swissprot | P11142 |
| Source | Mouse |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from the Internal region of human HSC 70. |
| Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213) |
| Recommended dilution | WB 1:500-1:2000, IHC 1:100-1:300 ELISA 1:40000 |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Cellular localization | Cytoplasm. Melanosome. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Tissue specificity | Ubiquitous. |
| Isotype | IgG |
| Purification | Protein A purification |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Background | This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
