HTR2B Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10115
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | 5 HT 2B,5 HT 2B receptor,5 HT(2B),5 HT2B,5 hydroxytryptamine (serotonin) receptor 2B,5 hydroxytryptamine (serotonin) receptor 2B G protein coupled,5 hydroxytryptamine 2B receptor,5 hydroxytryptamine receptor 2B,5-HT-2B,5-HT2B,5-hydroxytryptamine receptor 2B,5HT(2B),5HT2B,5HT2F,Htr 2b,Htr2b,NP75 protein,SEROTONIN 5HT2B RECEPTOR,Serotonin receptor 2B,Stomach fundus serotonin receptor,HTR2B抗体 |
| Swissprot | P41595 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human HTR2B |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 0.2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. |
| Tissue specificity | Expressed in brain. Higher levels of expression are observed in the cerebellum, occipital cortex and frontal cortex. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. |
