HTR3A Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-13884
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | 5 HT 3,5 HT3 receptor,5 HT3A,5 HT3A receptor,5 HT3RA,5 hydroxytryptamine (serotonin) receptor 3A,5-HT-3,5-HT3-A,5-HT3A,5-HT3R,5-hydroxytryptamine receptor 3,5-hydroxytryptamine receptor 3A,5HT receptor,5HT3 serotonin receptor,5HT3A,5HT3R,HTR3,Htr3a,Serotonin receptor 3A,Serotonin-gated ion channel receptor 3a,Serotonin-gated ion channel receptor,HTR3A抗体 |
| Swissprot | P46098 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human HTR3A |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell junction, synapse, postsynaptic cell membrane. Cell membrane. |
| Tissue specificity | Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. |
