HTRA2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18199
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | High temperature requirement protein A2,HTRA 2,HtrA like serine protease,HtrA serine peptidase 2,HtrA, E. coli, homolog of, 2,HtrA2,HTRA2,mitochondrial,Omi stress regulated endoprotease,Omi stress-regulated endoprotease,PARK 13,PARK13,Protease serine 25,PRSS 25,PRSS25,Serine protease 25,Serine protease HTRA2,Serine protease HTRA2 mitochondrial,Serine protease htra2 mitochondrial precursor,Serine protease omi,Serine proteinase OMI,HTRA2抗体 |
| Swissprot | O43464 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human HTRA2 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 1.2mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion intermembrane space. Mitochondrion membrane. Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment, and stimulation of mitochondria with caspase-8 truncated BID/tBID. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. |
