Hyaluronidase 1/HYAL1 Polyclonal Antibody(Capture/Detector)
| 规格： | / 25μg / 100μg |
| 价格： | / ￥800 / ￥2100 |
货号：AN000630P
货期：咨询
宿主: Rabbit
反应性: H
应用: ELISA Capture/Detector
Overview
| Synonyms | Hyaluronic Lase |
| Swissprot | Q12794 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant Human Hyaluronidase 1/HYAL1 protein expressed by Mammalian |
| Application | ELISA Capture/Detector |
| Recommended dilution | ELISA Capture,,2-8 μg/mL;ELISA Detector,,0.1-0.4 μg/mL |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C Valid for 1 month or -20°C Valid for 12 months,Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Storage buffer | Sterile PBS,pH 7.4 |
| Background | yaluronic acid (HA) is a glycosaminoglycan that is believed to have numerous important biologic functions,including modulation of cell proliferation,migration,and differentiation,as well as the regulation of extracellular water and protein homeostasis. It is also an integral structural component of cartilage and other tissues and acts as a lubricant in joints. Hyaluronidases are a family of enzymes that catalyse the degradation of HA. In humans,there are five functional hyaluronidases: HYAL1,HYAL2,HYAL3,HYAL4 and HYAL5 (also known as SPAM1 or PH-20); plus a pseudogene,HYAL6 (also known as HYALP1). HYAL-1 is present in many tissues and is predominantly found in the plasma and urine (PMID: 16600643). In addition to its function in normal cellular hyaluronan turnover,human HYAL-1 is implicated in cancer proliferation,angiogenesis,and inflammatory diseases |
