ICAM5 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-13316
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | ICAM5 precursor,Intercellular adhesion molecule 5,Intercellular adhesion molecule 5 precursor,Intercellular adhesion molecule 5,telencephalin,Telencephalin,TLCN,TLN,ICAM5抗体 |
| Swissprot | Q9UMF0 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Synthetic peptide of human ICAM5 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:200-1:1000; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane; single-pass type I membrane protein |
| Tissue specificity | Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. |
Images
Western Blot analysis of 293T and Hela cell using ICAM5 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human thyroid cancer using ICAM5 Polyclonal Antibody at dilution of 1:25
Immunohistochemistry of paraffin-embedded Human brain using ICAM5 Polyclonal Antibody at dilution of 1:25
