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IDH1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-14691

宿主: Rabbit

反应性: H,M,R

应用: WB,IHC

  • 详情
  • Overview

    Synonyms Cytosolic NADP isocitrate dehydrogenase,Cytosolic NADP-isocitrate dehydrogenase,Epididymis luminal protein 216,Epididymis secretory protein Li 26,HEL-216,HEL-S-26,ICDH,IDCD,IDH,IDH1,IDHC,IDP,IDPC,Isocitrate dehydrogenase (NADP(+)) 1 cytosolic,Isocitrate dehydrogenase [NADP] cytoplasmic,Isocitrate dehydrogenase 1 (NADP+) soluble,NADP dependent isocitrate dehydrogenase cytosolic,NADP dependent isocitrate dehydrogenase peroxisomal,NADP(+)-specific ICDH,Oxalosuccinate decarboxylase,PICD,IDH1抗体
    Swissprot O75874
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Recombinant protein of human IDH1
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:200-1:1000;IHC,,1:50-1:200;
    Concentration 0.7 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm. Peroxisome.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence.
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