IDH2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11319
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | D2HGA2,ICD-M,IDH,IDH2,IDHM,IDHP,IDP,IDPM,Isocitrate dehydrogenase [NADP],mitochondrial,Isocitrate dehydrogenase 2 (NADP+),mitochondrial,mNADP-IDH,NADP(+)-specific ICDH,Oxalosuccinate decarboxylase,IDH2抗体 |
| Swissprot | P48735 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human IDH2 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. |
Images
Western Blot analysis of Human fetal muscle tissue, Jurkat and 293T cell, Hela cell and Mouse liver tissue using IDH2 Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human cervical cancer using IDH2 Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human colon cancer using IDH2 Polyclonal Antibody at dilution of 1:60
