IDO2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18375
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | 3-dioxygenase 2,3-dioxygenase-like protein 1,EC 1.13.11.,I23O2,IDO 2,IDO-2,Ido2,INDOL 1,Indoleamine 2,Indoleamine 2,3 dioxygenase 2,Indoleamine 2,3 dioxygenase like 1 protein,Indoleamine 2,3 dioxygenase like protein 1,Indoleamine pyrrole 2,3 dioxygenase like 1,Indoleamine pyrrole 2,3 dioxygenase like protein 1,Indoleamine-pyrrole 2,IDO2抗体 |
| Swissprot | Q6ZQW0 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Full length fusion protein |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:30-1:150; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol,Other locations:cytoplasm |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1. |
