IDS Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19223
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | Alpha L iduronate sulfate sulfatase,Alpha-L-iduronate sulfate sulfatase,AW214631,Ids,IDS,Iduronate 2 sulfatase 14 kDa chain,Iduronate 2 sulfatase 42 kDa chain,Iduronate 2 sulfatase,Iduronate 2-sulfatase 14 kDa chain,Iduronate sulfatase,Idursulfase,MPS2,RP23-29M4.1,SIDS,IDS抗体 |
| Swissprot | P22304 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human IDS |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 1.02mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Lysosome. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome,an X chromosome-linked disease. An internal proteolytic cleavage occurs to produce the mature IDS present in human liver shown to contain a 42 kDa polypeptide N-terminal to a 14 kDa polypeptide.. |
