IFNAR1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40306
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | Alpha type antiviral protein,Antiviral protein,alpha-type,Antiviral protein,beta-type,AVP,Beta type antiviral protein,CRF2-1,Cytokine receptor class-II member 1,Cytokine receptor family 2 member 1,IFN alpha REC,IFN alpha receptor,IFN alpha/beta Receptor alpha,IFN beta receptor,IFN Interferon-beta receptor,IFN-alpha/beta receptor 1,IFN-R-1,IFNAR,Ifnar1,IFNBR,IFRC,INAR1,Interferon (alpha beta and omega) receptor 1,interferon alpha and beta receptor subunit 1,Interferon alpha/beta receptor 1,Interferon alpha/beta receptor alpha chain,Interferon beta receptor 1,interferon receptor 1,Interferon-alpha receptor,Type I interferon receptor 1,IFNAR1抗体 |
| Swissprot | P17181 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant Human Interferon alpha/beta receptor 1 protein |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC 1:100-1:300 |
| Concentration | 0.5mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane.Endosome.Lysosome. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.3. |
| Background | IFNAR1 (Interferon Alpha And Beta Receptor Subunit 1) is a Protein Coding gene. Diseases associated with IFNAR1 include Septicemic Plague and Hepatitis C. Among its related pathways are Type I Interferon Signaling Pathways and Immune response IFN alpha/beta signaling pathway. GO annotations related to this gene include interferon receptor activity and type I interferon receptor activity. An important paralog of this gene is ENSG00000249624.The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. |
