IFT74 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16349
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | intraflagellar transport 74,Chlamydomonas,homolog of,Capillary morphogenesis gene 1 protein,Capillary morphogenesis protein 1,Ccdc2,CMG 1,CMG-1,Coiled-coil domain containing 2,Coiled-coil domain-containing protein 2,IFT74,IFT74,intraflagellar transport 74 homolog (Chlamydomonas),intraflagellar transport 74 homolog,Intraflagellar transport protein 74 homolog,IFT74抗体 |
| Swissprot | Q96LB3 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human IFT74 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 1.2mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasmic vesicle. Intracellular vesicular compartment. |
| Tissue specificity | Highly expressed in adult and fetal kidney and expressed at lower level in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. Little to no expression was detected in adult brain and skeletal muscle or in fetal brain, thymus and spleen. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Capillary morphogenesis protein 1 (CMG1), also known as intraflagellar transport protein 74 (ITP74) or coiled-coil domain-containing protein 2 (CCDC2), is a 600 amino acid human homologue of IFT-71, a complex B protein supporting intraflagellar transport (IFT) in Chlamydomonas. CMG1 localizes to the cytoplasmic vesicle and is highly expressed in adult and fetal kidney and testis, with lower levels of expression in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. CMG1 has been suggested to have a role in the primary cilia of HUVEC, and it also functions as a transcriptional regulator of cyclin D2 in spermatocyte-derived cells. |
