IL1RAP Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-40454
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | C3orf13, FLJ37788, IL 1 receptor accessory protein, IL 1R3, IL 1RAcP, IL 1RAP, Interleukin 1 Accessory Protein, interleukin 1 receptor 3, Interleukin 1 receptor accessory protein,IL1RAP抗体 |
Swissprot | Q9NPH3 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant Human Interleukin-1 receptor accessory protein |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC 1:100-1:300 |
Concentration | 0.7mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Membrane, Secreted |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.3. |
Background | Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. |
Images
Immunohistochemistry of paraffin-embedded Human lung using IL1RAP Polycloanl Antibody at dilution of 1:150.
Immunohistochemistry of paraffin-embedded Mouse brain using IL1RAP Polycloanl Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded Rat brain using IL1RAP Polycloanl Antibody at dilution of 1:200.