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IL22RA1 Polyclonal Antibody

规格: / 60μL / 120μL / 200μL
价格: / ¥1380 / ¥2220 / ¥3300

货号:E-AB-70163

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms CRF2 9,CRF2-9,Cytokine receptor class-II member 9,cytokine receptor classII member 9,Cytokine receptor family 2 member 9,I22R1,IL-22 receptor subunit alpha-1,IL-22R-alpha-1,IL-22RA1,IL22R,IL22R1,Il22ra1,ILTIF R1 chain,Interleukin 22 Receptor alpha 1,Interleukin 22 Receptor,Interleukin-22 receptor subunit alpha-1,ZcytoR11,IL22RA1抗体
    Swissprot Q8N6P7,Q80XZ4
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen KLH conjugated Synthetic peptide corresponding to Mouse IL22RA1
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:200
    Concentration 440 μg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Plasma Membrane,Other locations:integral component of membrane
    Tissue specificity Expressed in colon, liver, lung, pancreas and kidney. No expression in immune cells such as monocytes, T-cells, and NK-cells. Expressed in keratinocytes of normal skin as well as in psoriatic skin lesion. Detected in normal blood brain barrier endothelial cells as well as in multiple sclerosis lesions; Strongly expressed on central nervous system vessels within infiltrated multiple sclerosis lesions. Overexpressed in synovial fluid cells from rheumatoid arthritis and spondyloarthropathy patients.Highest expression level in body of pancreas.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
    Background The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22).IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10).This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36.
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