IL22RA1 Polyclonal Antibody
规格: | / 60μL / 120μL / 200μL |
价格: | / ¥1380 / ¥2220 / ¥3300 |
货号:E-AB-70163
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | CRF2 9,CRF2-9,Cytokine receptor class-II member 9,cytokine receptor classII member 9,Cytokine receptor family 2 member 9,I22R1,IL-22 receptor subunit alpha-1,IL-22R-alpha-1,IL-22RA1,IL22R,IL22R1,Il22ra1,ILTIF R1 chain,Interleukin 22 Receptor alpha 1,Interleukin 22 Receptor,Interleukin-22 receptor subunit alpha-1,ZcytoR11,IL22RA1抗体 |
Swissprot | Q8N6P7,Q80XZ4 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse IL22RA1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:200 |
Concentration | 440 μg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Plasma Membrane,Other locations:integral component of membrane |
Tissue specificity | Expressed in colon, liver, lung, pancreas and kidney. No expression in immune cells such as monocytes, T-cells, and NK-cells. Expressed in keratinocytes of normal skin as well as in psoriatic skin lesion. Detected in normal blood brain barrier endothelial cells as well as in multiple sclerosis lesions; Strongly expressed on central nervous system vessels within infiltrated multiple sclerosis lesions. Overexpressed in synovial fluid cells from rheumatoid arthritis and spondyloarthropathy patients.Highest expression level in body of pancreas. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Background | The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22).IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10).This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. |
Images
Immunohistochemistry analysis of paraffin-embedded human colon using IL22RA1 Polyclonal Antibody at dilution of 1:200.
Immunohistochemistry analysis of paraffin-embedded human stomach using IL22RA1 Polyclonal Antibody at dilution of 1:200.
Immunohistochemistry analysis of paraffin-embedded mouse lung using IL22RA1 Polyclonal Antibody at dilution of 1:200.
Immunohistochemistry analysis of paraffin-embedded Rat spleen using IL22RA1 Polyclonal Antibody at dilution of 1:200.