IL2RA Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-12519
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
Synonyms | Interleukin 2 receptor alpha chain,CD25,CD25 antigen,IDDM10,IL 2 receptor alpha subunit,IL-2 receptor subunit alpha,IL-2-RA,IL-2R subunit alpha,IL2 RA,IL2-RA,IL2R,IL2R,alpha chain,IL2RA,IL2RA,IMD41,Interleukin 2 receptor alpha,Interleukin 2 receptor,Interleukin-2 receptor subunit alpha,p55,t-cell growth factor receptor,TAC,TAC antigen,TCGFR,IL2RA抗体 |
Swissprot | P01589 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human IL2RA |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:200-1:1000; |
Concentration | 0.3 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. |