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IL2RA Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-12519

宿主: Rabbit

反应性: H,M,R

应用: WB

  • 详情
  • Overview

    Synonyms Interleukin 2 receptor alpha chain,CD25,CD25 antigen,IDDM10,IL 2 receptor alpha subunit,IL-2 receptor subunit alpha,IL-2-RA,IL-2R subunit alpha,IL2 RA,IL2-RA,IL2R,IL2R,alpha chain,IL2RA,IL2RA,IMD41,Interleukin 2 receptor alpha,Interleukin 2 receptor,Interleukin-2 receptor subunit alpha,p55,t-cell growth factor receptor,TAC,TAC antigen,TCGFR,IL2RA抗体
    Swissprot P01589
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human IL2RA
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:200-1:1000;
    Concentration 0.3 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
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