IL6 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19453
宿主: Rabbit
反应性: H
应用: WB
Overview
Synonyms | Interleukin BSF 2,B cell differentiation factor,B cell stimulatory factor 2,B-cell stimulatory factor 2,BSF 2,BSF-2,BSF2,CDF,CTL differentiation factor,Hepatocyte stimulatory factor,HGF,HSF,Hybridoma growth factor,Hybridoma growth factor Interferon beta-2,IFN-beta-2,IFNB2,IL 6,IL-6,IL6,IL6,Interferon beta 2,Interferon beta-2,Interleukin 6,Interleukin 6 (interferon beta 2),Interleukin BSF 2,Interleukin-6,IL6抗体 |
Swissprot | P05231 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Synthetic peptide of human IL6 |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:500-1:2000; |
Concentration | 1.1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells,T-cells,hepatocytes,hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine,a cytokine produced from muscle,and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally,IL-6 is involved in hematopoiesis,bone metabolism,and cancer progression,and has been defined an essential role in directing transition from innate to acquired immunity. |