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IL6 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19453

宿主: Rabbit

反应性: H

应用: WB

  • 详情
  • 文献(1)
  • Overview

    Synonyms Interleukin BSF 2,B cell differentiation factor,B cell stimulatory factor 2,B-cell stimulatory factor 2,BSF 2,BSF-2,BSF2,CDF,CTL differentiation factor,Hepatocyte stimulatory factor,HGF,HSF,Hybridoma growth factor,Hybridoma growth factor Interferon beta-2,IFN-beta-2,IFNB2,IL 6,IL-6,IL6,IL6,Interferon beta 2,Interferon beta-2,Interleukin 6,Interleukin 6 (interferon beta 2),Interleukin BSF 2,Interleukin-6,IL6抗体
    Swissprot P05231
    Source Rabbit
    Reactivity Human
    Immunogen Synthetic peptide of human IL6
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:500-1:2000;
    Concentration 1.1mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Secreted.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells,T-cells,hepatocytes,hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine,a cytokine produced from muscle,and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally,IL-6 is involved in hematopoiesis,bone metabolism,and cancer progression,and has been defined an essential role in directing transition from innate to acquired immunity.
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