IL-29/IFN-λ1 Monoclonal Antibody(Capture/Detector)
| 规格： | / 25μg / 100μg |
| 价格： | / ￥800 / ￥2100 |
货号：AN001310P
货期：咨询
宿主: Mouse
反应性: H
应用: ELISA Capture/Detector
Overview
| Synonyms | InterLeukin-29(IL-29);IFNL1;ZCYTO21;Interferon Lambda-1;IFN-Lambda-1;Cytokine Zcyto21;IL29 |
| Swissprot | Q8IU54 |
| Source | Mouse |
| Reactivity | Human |
| Immunogen | Recombinant Human IL-29/IFN-λ1 protein expressed by Mammalian |
| Application | ELISA Capture/Detector |
| Recommended dilution | ELISA Capture,,2-8 μg/mL;ELISA Detector,,0.1-0.4 μg/mL |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | 1A6 |
|---|---|
| Isotype | IgG1 |
| Purification | Protein A/G Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C Valid for 1 month or -20°C Valid for 12 months,Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Storage buffer | Sterile PBS,pH 7.4 |
| Background | Cytokine with antiviral,antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense,predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of Il10RB and IFNlR1,and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG),which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNlR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression. |
