IMPDH1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16519
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | IMDH1,IMP (inosine monophosphate) dehydrogenase 1,IMP dehydrogenase 1,IMPD 1,IMPD,IMPD1,IMPDH 1,IMPDH I,IMPDH-I,Impdh1,Inosine 5' monophosphate dehydrogenase 1,Inosine monophosphate dehydrogenase 1,Inosine-5''-monophosphate dehydrogenase 1,LCA11,RP10,sWSS2608,IMPDH1抗体 |
| Swissprot | P20839 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human IMPDH1 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol,Extracellular region or secreted,extracellular region,Lysosome,azurophil granule lumen,Nucleus,Other locations:cytoplasm,ficolin-1-rich granule lumen,secretory granule lumen |
| Tissue specificity | IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. |
