INO80 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18113
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | DNA helicase INO80,hINO80,homolog of yeast INO80,INO80,INO80 complex subunit A,INO80 homolog,INO80,INO80A,INOC1,KIAA1259,Putative DNA helicase INO80 complex homolog 1,INO80抗体 |
| Swissprot | Q9ULG1 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human INO80 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:300 |
| Concentration | 2.46mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Colocalizes with PCNA at replication forks during S-phase. Recruited to DNA damage sites in a ACTR8-dependent manner. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a subunit of the chromatin remodeling complex, which is classified into subfamilies depending on sequence features apart from the conserved ATPase domain. This protein is the catalytic ATPase subunit of the INO80 chromatin remodeling complex, which is characterized by a DNA-binding domain. This protein is proposed to bind DNA and be recruited by the YY1 transcription factor to activate certain genes. Alternative splicing results in multiple transcript variants. |
