IPO8 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-16522
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | FLJ26580,Imp 8,Imp8,Importin-8,Importin8,IPO 8,IPO8,IPO8,Ran binding protein 8,RAN BP8,Ran-binding protein 8,RANBP 8,RanBP8,IPO8抗体 |
Swissprot | O15397 |
Source | Rabbit |
Reactivity | Human,Mouse |
Immunogen | Synthetic peptide of human IPO8 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:100-1:300 |
Concentration | 1.2mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm. Nucleus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |