ITGA3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18119
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | AA407068,Antigen identified by monoclonal J143,CD49 antigen like family member C,CD49 antigen-like family member C,CD49c,CD49c antigen,FLJ34631,FLJ34704,FRP 2,FRP-2,FRP2,Galactoprotein B3,GAP B3,GAPB3,Integrin alpha 3,Integrin alpha-3 light chain,Integrin,alpha 3 (antigen CD49C,alpha 3 subunit of VLA-3 receptor),ITA3,ITGA 3,Itga3,MSK18,VCA 2,VCA2,Very late activation protein 3 receptor alpha 3 subunit,VL3A,VLA 3 alpha chain,VLA 3 subunit alpha,VLA-3 subunit alpha,VLA3a,ITGA3抗体 |
| Swissprot | P26006 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human ITGA3 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:40-1:200 |
| Concentration | 1.32mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | ITGA3,also named as MSK18,CD49c,GAPB3 and FRP-2,belongs to the integrin alpha chain family. It is a receptor for fibronectin,laminin,collagen,epiligrin,thrombospondin and CSPG4. ITGA3 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. ITGA3 is highly concentrated in epithelial cells where it strongly adheres to Laminin-5 and Laminin-5 induced rapid adhesion can be blocked by antibodies against the alpha-3 integrin subunit. It can be cleaved into heavy chain(840aa) and light chain(176aa). This antibody can recognize the heavy chain. |
