ITGB2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-15140
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
Synonyms | 95 subunit beta,Beta 2 (antigen CD18 (p95),CD 18,CD18,Cell surface adhesion glycoprotein LFA 1/CR3/P150,959 beta subunit precursor),Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta,Cell surface adhesion glycoproteins LFA-1/CR3/p150,Complement component 3 receptor 3 and 4 subunit,Complement receptor C3 beta subunit,Complement receptor C3 subunit beta,Integrin beta 2,Integrin beta chain beta 2,Integrin beta-2 (ITGB2),Integrin beta-2,Integrin,beta 2 (complement component 3 receptor 3 and 4 subunit),ITB2,ITGB2,LAD,LCAMB,Leukocyte associated antigens CD18/11A,CD18/11B,CD18/11C,Leukocyte cell adhesion molecule CD18,LFA 1,LFA1,Lymphocyte function associated antigen 1 (LFA1),Lymphocyte function associated antigen 1,MAC 1,MAC1,Macrophage antigen 1 (mac1) beta,MF17,MFI7,OTTHUMP00000115278,OTTHUMP00000115279,OTTHUMP00000115280,OTTHUMP00000115281,OTTHUMP00000115282,ITGB2抗体 |
Swissprot | P05107 |
Source | Rabbit |
Reactivity | Human,Mouse |
Immunogen | Recombinant protein of human ITGB2 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:25-1:100; |
Concentration | 0.3 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Membrane. |
Tissue specificity | Leukocytes (PubMed:23775590). Expressed in neutrophils (at protein level) (PubMed:21193407, PubMed:28807980). |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine witHuman, Mouseultiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. |