ITLN1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15143
宿主: Rabbit
反应性: H,M
应用: WB
Overview
| Synonyms | Endothelial lectin HL 1,Endothelial lectin HL-1,FLJ20022,Galactofuranose binding lectin,Galactofuranose-binding lectin,hIntL,HL 1,HL1,Intelectin,Intelectin 1,Intelectin-1,Intestinal lactoferrin receptor,INTL,ITLN,ITLN-1,ITLN1,ITLN1,LFR,Omentin,OTTHUMP00000027882,ITLN1抗体 |
| Swissprot | Q8WWA0 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human ITLN1 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:1000-1:5000; |
| Concentration | 0.2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Secreted. Enriched in lipid rafts. |
| Tissue specificity | Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level). Highly expressed in the small intestine. Also found in the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid and, to a lesser degree, in the uterus, spleen, prostate, lymph node and thymus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Intelectin-1 also known as the intestinal lactoferrin receptor is a protein that in humans is encoded by the ITLN1 gene.Intelectin-1 functions both as a receptor for bacterial arabinogalactans and for lactoferrin.Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes.Increases AKT phosphorylation in the absence and presence of insulin.May play a role in the defense system against microorganisms.May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. |
