JMJD6 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70209
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | Apoptotic cell clearance receptor,Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6,Histone arginine demethylase JMJD6,JmjC domain-containing protein 6,JMJD 6,JMJD6,JMJD6,Jumonji domain containing 6,Jumonji domain-containing protein 6,KIAA0585,Lysyl-hydroxylase JMJD6,Peptide-lysine 5-dioxygenase JMJD6,Phosphatidylserine receptor,Protein PTDSR,PSR,PTDSR 1,PTDSR,PTDSR1,JMJD6抗体 |
| Swissprot | Q6NYC1,Q9ERI5,Q6AYK2 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse JMJD6 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:500-1:2000; |
| Concentration | 0.76 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus>nucleoplasm. Nucleus>nucleolus. Mainly found throughout the nucleoplasm outside of regions containing heterochromatic DNA, with some localization in nucleolus. During mitosis, excluded from the nucleus and reappears in the telophase of the cell cycle. |
| Tissue specificity | Highly expressed in the heart, skeletal muscle and kidney. Expressed at moderate or low level in brain, placenta, lung, liver, pancreas, spleen, thymus, prostate, testis and ovary. Up-regulated in many patients with chronic pancreatitis. Expressed in nursing thymic epithelial cells.Highest expression level in blood. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene. |
Images
Immunohistochemistry analysis of paraffin-embedded human colon cancer using JMJD6 Polyclonal Antibody at dilution of 1:1000.
mmunohistochemistry analysis of paraffin-embedded human stomach cancer using JMJD6 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded mouse kidney using JMJD6 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded rat heart using JMJD6 Polyclonal Antibody at dilution of 1:1000.
