KCNQ5 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11349
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | KCNQ 5,KCNQ5,KCNQ5,KQT like 5,KQT-like 5,Kv7.5,OTTHUMP00000064152,OTTHUMP00000064153,Potassium channel alpha subunit KvLQT5,Potassium channel protein,Potassium channel subunit alpha KvLQT5,Potassium voltage gated channel KQT like subfamily member 5,Potassium voltage gated channel subfamily KQT member 5,Potassium voltage-gated channel subfamily KQT member 5,Voltage gated potassium channel subunit Kv7.5,Voltage-gated potassium channel subunit Kv7.5,KCNQ5抗体 |
| Swissprot | Q9NR82 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human KCNQ5 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:25-1:100 |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | Strongly expressed in brain and skeletal muscle. In brain, expressed in cerebral cortex, occipital pole, frontal lobe and temporal lobe. Lower levels in hippocampus and putamen. Low to undetectable levels in medulla, cerebellum and thalamus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common witHuman, Mouse-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. |
