KIF3A Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10420
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | KIF 3,KIF 3A,KIF3,Kif3a,KIF3A,Kifl,Kinesin family member 3A,Kinesin family protein 3,Kinesin family protein 3A,Kinesin like protein KIF 3A,Kinesin like protein KIF3A,Kinesin-like protein KIF3A,Kns3,Microtubule plus end directed kinesin motor 3A,Microtubule plus end-directed kinesin motor 3A,KIF3A抗体 |
| Swissprot | Q9Y496 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human KIF3A |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:200-1:1000; |
| Concentration | 0.2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm>cytoskeleton. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Kinesin-like protein KIF3A is a protein that in humans is encoded by the KIF3A gene.Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C.KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis.KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined.Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate. |
Images
Western Blot analysis of Mouse brain and Human fetal brain tissue, Human brain malignant glioma tissue using KIF3A Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human thyroid cancer using KIF3A Polyclonal Antibody at dilution of 1:25
Immunohistochemistry of paraffin-embedded Human lung cancer using KIF3A Polyclonal Antibody at dilution of 1:25
