KRCC1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19203
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | CHBP2,cryptogenic hepatitis binding protein,Cryptogenic hepatitis-binding protein 2,KRCC1,KRCC1,lysine rich coiled coil 1,Lysine-rich coiled-coil protein 1,KRCC1抗体 |
| Swissprot | Q9NPI7 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human KRCC1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300; |
| Concentration | 1.68mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | KRCC1 (lysine-rich coiled-coil 1), also known as CHBP2 (cryptogenic hepatitis-binding protein 2), is a 259 amino acid protein that is encoded by a gene located on human chromosome 2p11.2.Consisting of 237 million bases, chromosome 2 is the second largest human chromosome and encodes over 1,400 genes.A number of genetic diseases are linked to genes on chromosome 2.Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene.The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8.An extremely rare recessive genetic disorder, Alstr m syndrome, is due to mutations in the ALMS1 gene.Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. |
