L1CAM Polyclonal Antibody
规格: | / 50μL / 100μL |
价格: | / ¥1010 / ¥1640 |
货号:D-AB-10196L
货期:咨询
宿主: Rabbit
反应性: M,R
应用: WB,IHC
Overview
Synonyms | Antigen identified by monoclonal antibody R1, CAML1, CD171, CD171 antigen, HSAS, HSAS1, Hyd, L1 cell adhesion molecule, L1, MASA, L1cam, MIC5, NCAML1, Nerve-growth factor-inducible large external glycoprotein, Neural cell adhesion molecule L1, NILE, OTTHUMP00000025992, S10, SPG1 |
Swissprot | P11627 |
Source | Rabbit |
Reactivity | Mouse,Rat |
Immunogen | Recombinant Mouse L1cam protein expressed by E.coli |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:1000; |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane, Cell projection |
Isotype | IgG |
Purification | Antigen Affinity Purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
Background | The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. |
Images
Western blot with EEF2 Polyclonal antibody at dilution of 1:500.lane 1:A431 whole cell lysate,lane 2:Hela whole cell lysate,lane 3:NIH/3T3 whole cell lysate,lane 4: C6 whole cell lysate,Lane 5:PC-12 whole cell lysate
Immunohistochemistry of paraffin-embedded Mouse brain using L1CAM Polycloanl Antibody at dilution of 1:300.
Immunohistochemistry of paraffin-embedded Rat brain using L1CAM Polycloanl Antibody at dilution of 1:300.