LASP1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-52366
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | LASP 1,LASP-1,LASP1,LASP1,LIM and SH3 domain protein 1,LIM and SH3 protein 1,Metastatic lymph node gene 50 protein,MLN 50,MLN50,OTTHUMP00000164238,OTTHUMP00000164239,LASP1抗体 |
Swissprot | Q14847 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Full length fusion protein |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:25-1:100; |
Concentration | 0.8mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm>cell cortex. Cytoplasm>cytoskeleton. Associated with the F-actin rich cortical cytoskeleton. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. |