LDHA Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18030
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Cell proliferation-inducing gene 19 protein,L lactate dehydrogenase A chain,Lactate dehydrogenase A,LDH A,LDH M,LDH muscle subunit,LDH1,LDH5,LDHA,PIG 19,PIG19,Renal carcinoma antigen NY-REN-59,LDHA抗体 |
| Swissprot | P00338 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human LDHA |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:30-1:150; |
| Concentration | 0.72mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasmic |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa. |
Images
Western blot analysis of 293T and A375 cell lysates using LDHA Polyclonal Antibody at dilution of 1:250
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using LDHA Polyclonal Antibody at dilution of 1:25(×200)
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using LDHA Polyclonal Antibody at dilution of 1:25(×200)
