LDHA Polyclonal Antibody
| 规格： | / 50μL / 100μL |
| 价格： | / ￥1010 / ￥1640 |
货号：D-AB-10210L
货期：咨询
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Cell proliferation-inducing gene 19 protein, GSD11, L lactate dehydrogenase A chain, l7R2, LDH M, LDH muscle subunit, LDH1, PIG19 Proliferation-inducing gene 19 |
| Swissprot | P00338 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant Human LDHA protein expressed by E.coli |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:2500-1:5000;IHC,,1:200-1:400; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm |
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa. |
Images
Western blot with CD44 Polyclonal antibody at dilution of 1:500.lane 1:A549 whole cell lysate,lane 2:Hela whole cell lysate,lane 3:RAW264.7 whole cell lysate,lane 4: Mouse spleen,Lane 5:Rat spleen
Immunohistochemistry of paraffin-embedded Human liver cancer using LDHA Polyclonal Antibody at dilution of 1:400
