LDL Monoclonal Antibody(Detector)
规格: | / 25μg / 100μg |
价格: | / ¥800 / ¥2100 |
货号:AN001910P
货期:咨询
宿主: Mouse
反应性: H
应用: ELISA Detector
Overview
Synonyms | LDL;Low-Density Lipoprotein; |
Source | Mouse |
Reactivity | Human |
Immunogen | Human LDL Native Protein |
Application | ELISA Detector |
Recommended dilution | ELISA Detector,,0.1-0.4 μg/mL |
Concentration | 1mg/mL |
Clonality | Monoclonal |
Properties
Clone No | 4E1 |
---|---|
Isotype | IgG2a |
Purification | Protein A/G Purification |
Conjugation | Unconjugated |
Storage instructions | Store at 4°C Valid for 1 month or -20°C Valid for 12 months,Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
Storage buffer | Sterile PBS,pH 7.4 |
Background | The low density lipoprotein (LDL) receptor system coordinates the metabolism of cholesterol,an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation--the process of receptor-mediated endocytosis. Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits. It has been shown that the family of LDL receptors may serve as viral receptors. |