LDLR Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70239
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | FH,FHC,LDL R,LDL receptor,LDLCQ2,Ldlr,LDLR,Low Density Lipoprotein Receptor,Low density lipoprotein receptor class A domain containing protein 3,Low density lipoprotein receptor familial hypercholesterolemia,Low-density lipoprotein receptor,LDLR抗体 |
| Swissprot | P01130,P35951,P35952 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to LDL Receptor |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:1000 |
| Concentration | 1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane, Coated pit, Endosome, Golgi apparatus, LDL, Lysosome, Membrane |
| Tissue specificity | Highest expression level in cumulus cell |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits,which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE. |
Images
Immunohistochemistry analysis of paraffin-embedded human Lymphoma using LDLR Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded mouse thymus using LDLR Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat liver using LDLR Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat spleen using LDLR Polyclonal Antibody at dilution of 1:300.
