LDOC1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15168
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | BCUR1,Breast cancer up regulated 1,Breast cancer upregulated 1,Gm366,Ldoc1,LDOC1,Leucine zipper down regulated in cancer 1,Leucine zipper protein down regulated in cancer cells,Leucine zipper protein down regulated in cancer cells,Leucine zipper protein down-regulated in cancer cells,Mar7,Mart7,Protein LDOC1,RGD1565644,LDOC1抗体 |
| Swissprot | O95751 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human LDOC1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Tissue specificity | Ubiquitously expressed with high levels in brain ant thyroid and low expression in placenta, liver and leukocytes. Expressed as well in six of the seven human breast cancer cell lines examined. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. |
