LPAR2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12919
宿主: Rabbit
反应性: H,M
应用: IHC,ELISA
Overview
| Synonyms | EDG 4,EDG-4,EDG4,Endothelial Cell Differentiation Gene 4,Endothelial differentiation lysophosphatidic acid G protein coupled receptor 4,FLJ93869,G protein coupled receptor,IPA2,LPA 2,LPA receptor 2,LPA receptor EDG4,LPA-2,LPA2,LPAR2,LPAR2,Lysophosphatidic acid receptor 2,Lysophosphatidic acid receptor Edg 4,Lysophosphatidic acid receptor Edg-4,Lysophosphatidic acid receptor EDG4,LPAR2抗体 |
| Swissprot | Q9HBW0 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Synthetic peptide of human LPAR2 |
| Application | IHC(Detection kit: E-IR-R213),ELISA |
| Recommended dilution | IHC 1:25-1:100 |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell surface. Cell membrane. Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA colocalizes with RALA in the endocytic vesicles. |
| Tissue specificity | Expressed most abundantly in testes and peripheral blood leukocytes with less expression in pancreas, spleen, thymus and prostate. Little or no expression in heart, brain, placenta, lung, liver, skeletal muscle, kidney, ovary, small intestine, or colon. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. |
