LPXN Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18825
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | LDLP ,LDPL ,leupaxin,LPXN抗体 |
Swissprot | O60711 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Fusion protein of human LPXN |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:30-1:150 |
Concentration | 1.02mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell Membrane, Cytoplasmic and Nuclear |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |