LRIG1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12544
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | Leucine rich repeat protein,Leucine rich repeat protein LRIG1,leucine rich repeats and immunoglobulin like domains 1,Leucine-rich repeats and immunoglobulin-like domains protein 1,leucine-rich repeats- and immunoglobulin-like domains-cotnaining protein 1,LIG 1,LIG-1,LIG1,Lrig1,LRIG1,Ortholog of mouse integral membrane glycoprotein LIG 1,LRIG1抗体 |
| Swissprot | Q96JA1 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human LRIG1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | Widely expressed. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Leucine-rich repeats and immunoglobulin-like domains protein 1 is a protein that in humans is encoded by the LRIG1 gene.It encodes a transmembrane protein that has been shown to interact with receptor tyrosine kinases of the EGFR-family , MET and RET.Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation. |
