LXN Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10437
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | ECI,Endogenous carboxypeptidase inhibitor,Latexin,Latexin protein,LXN,LXN,MUM,Protein MUM,TCI,Tissue carboxypeptidase inhibitor,LXN抗体 |
| Swissprot | Q9BS40 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human LXN |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000; |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. |
| Tissue specificity | Highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Latexin, also designated endogenous carboxypeptidase inhibitor (ECI) or tissue carboxypeptidase inhibitor (TCI), belongs to the protease inhibitor I47 family of proteins. Latexin acts as a non-competitive, reversible inhibitor for metallocarboxypeptidases (MCPs), including CPA1, CPA2 and CPA4. It is a cytoplasmic protein that is highly expressed in heart, prostate, pancreas, ovary, kidney, brain and colon. Latexin consists of two topologically equivalent subdomains that bind to MCPs with low specificity, which gives it with the flexibility to inhibit all vertebrate A/B MCPs. |
Images
Western Blot analysis of A549 cell using LXN Polyclonal Antibody at dilution of 1:667
Immunohistochemistry of paraffin-embedded Human cervical cancer using LXN Polyclonal Antibody at dilution of 1:25
Immunohistochemistry of paraffin-embedded Human thyroid cancer using LXN Polyclonal Antibody at dilution of 1:25
