LXR alpha Polyclonal Antibody
规格: | / 60μL / 120μL / 200μL |
价格: | / ¥1380 / ¥2220 / ¥3300 |
货号:E-AB-70218
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
Synonyms | Liver X receptor alpha,LXR a,LXRA,NR1H3,NR1H3,Nuclear receptor subfamily 1 group H member 3,Oxysterols receptor LXR alpha,Oxysterols receptor LXR-alpha,RLD 1,RLD1,LXR alpha抗体 |
Swissprot | Q9Z0Y9,Q62685 |
Source | Rabbit |
Reactivity | Mouse,Rat |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse LXRα |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:400-1:1500 |
Concentration | 0.53 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. |
Tissue specificity | ighest expression level in thymus |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Background | NR1H3,also known as LXRA,is a liver X receptors,which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function,controlling transcriptional programs involved in lipid homeostasis and inflammation.. It's also a ligand-activated LXRs and forms heterodimers with retinoid X receptor,then participates in regulating expression of target genes containing LXR response elements. |