MAD2L1BP Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10441
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | Caught by MAD2 protein,CMT2,dJ261G23.1,KIAA0110,MAD2L1 binding protein,MAD2L1 binding protein isoform 2,MAD2L1-binding protein,Mad2l1bp,MD2BP,MGC11282,OTTHUMP00000016496,RP1 261G23.6,MAD2L1BP抗体 |
| Swissprot | Q15013 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human MAD2L1BP |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 0.8 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cytoplasm>cytoskeleton>spindle. During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
