MAGEA3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12753
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | Antigen MZ2 D,Antigen MZ2-D,Cancer/testis antigen 1.3,Cancer/testis antigen family 1 member 3,CT1.3,HIP8,HYPD,MAGA3,MAGE 3 antigen,MAGE family member A3,MAGE-3 antigen,MAGE3,MAGEA3,MAGEA6,Melanoma antigen family A 3,Melanoma associated antigen 3,Melanoma-associated antigen 3,MGC1461,MAGEA3抗体 |
| Swissprot | P43357 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human MAGEA3 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Endoplasmic reticulum,endoplasmic reticulum |
| Tissue specificity | Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta. Never expressed in kidney tumors, Leukemias and lymphomas. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. |
Images
Western Blot analysis of Human testis tissue, A549 and PC3 cell using MAGEA3 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human tonsil using MAGEA3 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human liver cancer using MAGEA3 Polyclonal Antibody at dilution of 1:50
