MAP1LC3B Monoclonal Antibody
| 规格： | / 20μL / 60μL / 120μL |
| 价格： | / ￥580 / ￥1420 / ￥2310 |
货号：E-AB-22132
宿主: Mouse
反应性: H
应用: IHC-p
Overview
| Synonyms | ATG8F,Autophagy-related protein LC3 B,Autophagy-related ubiquitin-like modifier LC3 B,LC3B,LC3II,MAP1 light chain 3 like protein 2,MAP1 light chain 3-like protein 2,MAP1A/1BLC3,MAP1A/MAP1B LC3 B,MAP1A/MAP1B light chain 3 B,MAP1ALC3,MAP1LC3B a,Map1lc3b,Microtubule associated protein 1 light chain 3 beta,Microtubule-associated protein 1 light chain 3 beta,Microtubule-associated proteins 1A/1B light chain 3B,MLP3B,LC3B Mouse (9H5)抗体 |
| Swissprot | Q9GZQ8 |
| Source | Mouse |
| Reactivity | Human |
| Immunogen | Recombinant Protein of LC3B of MAP1LC3B |
| Application | IHC-p(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-200 |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Cellular localization | Cytoplasm>cytoskeleton. Endomembrane system. Cytoplasmic vesicle>autophagosome membrane. LC3-II binds to the autophagic membranes. |
| Tissue specificity | Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver. |
| Clone No | Clone:6E4 |
|---|---|
| Isotype | IgG |
| Purification | Protein A purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Background | The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. MAP1LC3B (Microtubule Associated Protein 1 Light Chain 3 Beta) is a Protein Coding gene. Diseases associated with MAP1LC3B include Sporadic Pheochromocytoma and Lacrimal Gland Adenocarcinoma. Among its related pathways are Vesicle-mediated transport and Senescence and Autophagy in Cancer. GO annotations related to this gene include microtubule binding. An important paralog of this gene is MAP1LC3B2. |
