MAP2K1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16020
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Dual specificity mitogen activated protein kinase kinase 1,Dual specificity mitogen-activated protein kinase kinase 1,ERK activator kinase 1,MAP kinase kinase 1,MAP kinase/Erk kinase 1,MAP2K1,MAPK/ERK kinase 1,MAPKK 1,MAPKK1,MEK 1,Mek1,MEKK1,Mitogen activated protein kinase kinase 1,MKK 1,MKK1,MP2K1,PRKMK1,Protein kinase mitogen activated kinase 1 (MAP kinase kinase 1),Protein kinase mitogen activated,kinase 1,MAP2K1抗体 |
| Swissprot | Q02750 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human MAP2K1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoskeleton,microtubule organizing center,Cytosol,Endoplasmic reticulum,endoplasmic reticulum,Endosome,early endosome,late endosome,Extracellular region or secreted,extracellular exosome,Golgi apparatus,Golgi apparatus,Mitochondrion,Nucleus,Plasma Membrane,Other locations:focal adhesion |
| Tissue specificity | Widely expressed, with extremely low levels in brain. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. |
Images
Western Blot analysis of Jurkat, hela and K562 cell using MAP2K1 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human colon cancer using MAP2K1 Polyclonal Antibody at dilution of 1:25
Immunohistochemistry of paraffin-embedded Human ovarian cancer using MAP2K1 Polyclonal Antibody at dilution of 1:25
