MAP4K2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14677
宿主: Rabbit
反应性: H,M
应用: WB
Overview
| Synonyms | B lymphocyte serine/threonine protein kinase,B lymphocyte serine/threonine-protein kinase,BL44,GC kinase,GCK,Germinal center kinase,germinal centre kinase (GC kinase),M4K2,Map4k2,MAPK/ERK kinase kinase kinase 2,MEK kinase kinase 2,MEKKK 2,Mitogen activated protein kinase kinase kinase kinase 2,Mitogen-activated protein kinase kinase kinase kinase 2,Rab8 interacting protein,Rab8 interacting protein,formerly,Rab8-interacting protein,RAB8IP,RAB8IP,formerly,MAP4K2抗体 |
| Swissprot | Q12851 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human MAP4K2 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Basolateral cell membrane. Golgi apparatus membrane. |
| Tissue specificity | Highly expressed in germinal center but not mantle zone B-cells. Also expressed in lung, brain and placenta and at lower levels in other tissues examined. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a member of the serine/threonine protein kinase family.Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation.This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases.This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. |
