MBL2/MBP-C Polyclonal Antibody
| 规格： | / 25μL / 100μL |
| 价格： | / ￥800 / ￥2100 |
货号：D-AB-10438L
货期：咨询
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | COLEC 1;COLEC1;Collectin-1;HSMBPC;Lectin;mannose-binding;soluble;2;Mannan binding lectin;Mannan binding protein;Mannan-binding protein;Mannose binding lectin (protein C) 2 soluble;Mannose binding lectin (protein C) 2;soluble (opsonic defect);Mannose binding lectin (protein C) 2;soluble;Mannose binding lectin 2 soluble;Mannose binding lectin 2;soluble (opsonic defect);Mannose binding lectin;Mannose binding lectin protein C2 soluble opsonic defect;Mannose binding protein;Mannose binding protein C;Mannose binding protein C precursor;Mannose binding protein;serum;Mannose-binding lectin;Mannose-binding protein C;MBL 2;MBL;MBL2;MBL2;MBL2D;MBP 1;MBP;MBP C;MBP-C;MBP1;MBPB;MBPC;MBPD;MGC116832;MGC116833;Opsonic defect;protein C;Soluble mannose binding lectin |
| Swissprot | P11226 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant Human MBL2/MBP-C protein expressed by E.coli |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:1000 |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted |
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% BSA and 50% glycerol,pH7.4 |
| Background | Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix. Once released in serum,it further polymerizes forming dimers to octamers. The degree of serum polymerization is critical for the biological activity of MBL. MBL has higher affinity to microbial polysaccharides or their glycoconjugates. MBL was shown earlier to bind cell surfaces of bacteria,fungi,protozoa and viruses and acts as an acute-phase plasma protein (APP) during infection and inflammation. MBL activates the lectin-complement pathway,promotes opsonophagocytosis and modulates inflammation. |
